Professor Juan J. Calvete
obtained his education at University of Valencia
(from which he graduated in biochemistry in 1981) and University
of Madrid (where he defended his doctoral thesis in biochemistry
in 1985). Later, he held a number of postdoctoral positions:
in 1986 at INSERM U63, Lyon (France), in 1987 at Banting
Institute, Toronto (Canada) and, in the period of 1988 -
1989, at the Max-Planck-Institute in Munich (Germany), where
he was working as Invited Scientist in the years 1989 - 1992.
and, finally, in the period of 1993-1998, he was active in
the position of Researcher at the Veterinary High School
in Hannover, Germany. In 1989 Prof. Calvete obtained the
position of the Established Investigator of the Spanish Research
Council (CSIC), whereas in the period of 1993-1998 he worked
as the Established Investigator of the Veterinary High School
of Hannover, Germany.
At present, Prof. Calvete holds the
positions of Established Investigator and Head of the Structural
Proteomics Laboratory at the University of Valencia.
Among
other honours, Prof. Calvete obtained the Young Scientist
Award of the International Society on Thrombosis and Haemostasis
in 1989 .
Scientific interests of Prof. Juan J. Calvete
encompass:
-Venomics: Structural and functional proteomics
of disintegrins (snake venom integrin receptor antagonists)and
structural diversification of proteins by disulphide
bond engineering.
-Structural biology of carbohydrate-binding
proteins: spermadhesins (sperm surface-coating lectins
involved in sperm physiology) and plant lectins.
-Proteomic
analysis of human pathologies: Multiple myeloid leukemia,
cardiovascular diseases.
-Non-conventional Proteomics: Mass
spectrometric characterization of conformational features
of proteins: autoimmune diseases.
Prof. Calvete is the author
and co-author of numerous publications in highly-noted
scientific journals: Biochemistry, Biochem.J.,
Thromb. Haemostas. J. Biol. Chem., Cancer Res., J. Lab.
Invest., FEBS Lett., Platelets, Proteomics.